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Minor side effects are appetite loss, drowsiness, diarrhea, metallic taste, headaches, stomach upset and vomiting. Metronidazole should be used with caution in patients with active or chronic severe peripheral and central nervous system diseases due to the risk of neurological aggravation. Metronidazole antibiotic is marketed by Pfizer under the trade name Flagyl, and also by various generic manufacturers, who sell it at a cheaper price. Minor side effects are appetite loss, drowsiness, diarrhea, metallic taste, headaches, stomach upset and vomiting.