Prednisone has very little mineral corticoid activity, so it is not used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly. It works by modifying the body's immune response to various conditions and decreasing inflammation. Prednisone typically does not produce immediate effects and must be used for several weeks or even months at a time to get a chronic process under control. Corticosteroid. As effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired.
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