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Synthroid instructions use: "Side effects produced by Synthroid include fatigue, increased appetite, weight loss, heat intolerance, and fever. Synthroid may cause seizures at the beginning of treatment, although this is rare. Synthroid can interact with a wide variety of doses that allows for individualized treatment. It is important to take it regularly at the same time every day. Synthroid is the number one prescribed treatment for thyroid disease, in conditions where the thyroid gland. Common side effects produced by Synthroid include fatigue, increased appetite, weight loss, heat intolerance, and fever. Differences of only a few micrograms of Synthroid can make a large difference in how you feel."